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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. Prednisone 10 mg orally daily is prescribed for a 68-year-old 60-kg patient with acute temporal arteritis. The pharmacotherapy specialist would recommend which of the following?

A) Prednisone should be discontinued after 2 Weeks.
B) Dose should be increased to 60 mg daily.
C) Dose should be decreased to 5 mg daily.
D) Dose should be increased to 20 mg daily.

2. The most efficient approach for comparing the efficacy of treatments for BPH is to search which of the following?

A) MEDLINE for clinical trials
B) Cochrane Systematic Reviews
C) Lexicomp's Drug information Handbook
D) Drug Facts & Comparisons

3. In order to assess the effect of a potential metabolic enzyme inhibitor on the clearance of warfarin, the most appropriate study design would be which of the following?

A) Single-phase study with comparison of warfarin clearance to a population average in the literature
B) Double-blind, two-group parallel, controlled study
C) Randomized crossover study with a washout period between phases
D) Single-blind (investigator only), two-group parallel, controlled study

4. Post myocardial infarction, a patient's cardiac profile and serum chemistry results show the following values:
Heart rate: 120 bpm
Blood pressure: 80/40 mm Hg
Pulmonary capillary Wedge pressure: 6 mm Hg
Right atrial pressure: 2 mm Hg
Cardiac index: 2.3 L/min/m2
Sodium: 136 mEq/L
Potassium: 4.2 mEq/L
Chloride: 98 mEq/L
Bicarbonate: 22 mEq/L
Blood urea nitrogen: 25 mg/dL
Creatinine: 1.0 mg/dL
Glucose: 110 mg/dL
Which one of the following therapeutic regimens is most appropriate for the initial treatment of this patient?

A) Furosemide 40 mg intravenous push
B) Dopamine 15 mcg/kg/min
C) Normal saline 500 mL/h
D) Nitroprusside 2 mcg/kg/min

5. A 60-year-old man is admitted to the CCU with an acute anterior wall Ml. Therapy with amiodarone is initiated. The man's concurrent medications include Warfarin, furosemide, and enalapril. Which of the following baseline laboratory land clinical data, in addition to thyroid and liver function tests, should be obtained prior to initiation of amiodarone therapy in this patient?

A) Spirometry and 24-hour urine for creatinine clearance
B) Chest X-ray
C) Fasting blood glucose
D) FEV1 and baseline electroencephalogram

Solutions: